Molecular dynamics simulations of a helicase
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چکیده
منابع مشابه
Designing a new tetrapeptide to inhibit the BIR3 domain of the XIAP protein via molecular dynamics simulations
The XIAP protein is a member of apoptosis proteins family. The XIAP protein plays a central role in the inhibition of apoptosis and consists of three Baculoviral IAP Repeat domains. The BIR3 domain binds directly to the N-terminal of caspase-9 and therefore it inhibits apoptosis. N-terminal tetrapeptide region of SMAC protein can bind to BIR3, inhibit it and subsequently induce apoptosis. In th...
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ژورنال
عنوان ژورنال: Proteins: Structure, Function, and Genetics
سال: 2003
ISSN: 0887-3585,1097-0134
DOI: 10.1002/prot.10400